An orphaned boy learns responsibility, commitment and friendship when he is hired byi a heartless, wealthy sportsmani to train his handsome Irish setter, Big Red. Soon, the boy and the dog become inseparable, much to thei owner's disapproval and the boy is fired. But the bonds of loyalty are tested when Big Red runs away and all hope is lost of ever finding him again. The strong bond that exists among man, boy and dog lead them into a series of adventures, setting the course for a life-or-death battle with an unexpected adversary...