An advertising executive who just wants to fly home to spend Thanksgiving with his family is stuck with a loud but loveable salesman during an unbelievable succession of blizzards, transfers, strikes and delays. Two businessmen travelling from New York to Chicago get sidetracked in a public transportation nightmare. Neal is a stuffy ad executive who doesn't get along with people like the portly, gregarious salesman who sits next to him on the plane to Chicago. But when their flight is rerouted, the unlikely duo becomes entangled in a series of hilarious misadventures as they attempt to get home before Thanksgiving. They have to deal with sleazy motels, run-down rent-a-cars and crazy cabbies. It's enough to make them swear off travel forever!